Rivaroxaban, a blood-thinning medication sold under the brand name Xarelto®, is manufactured by Bayer and Janssen Pharmaceuticals. Doctors prescribe it to some patients to help prevent blood clots and strokes. While the manufacturer offers us a medical tool, ongoing litigation raises concerns about its potential for serious, and sometimes fatal, bleeding events.
Let us consider the example of Arkansas in the US. The death rate of strokes in the US is high, with Arkansas being among those states that lead. The stroke death rate is found to be 125 people per 100,000 of ages 35 and above. Heart disease is the leading mortality cause in Arkansas, as per the National Center for Health Statistics.
Stroke is a prevalent health concern in the US, occurring at an alarming rate of one case every 40 seconds. In Arkansas itself, around 30 people are hospitalized from this disease each day. Let’s explore potential dangers of Rivaroxaban (Xarelto®) and the legal options available to Arkansans who may have been harmed by this medication.
Increased Risk of Bleeding with Xarelto®
Unlike older blood thinners like Warfarin, Xarelto® lacks a readily available reversal agent to stop uncontrollable bleeding. This can be particularly dangerous for patients who experience complications during surgery, accidental injuries, or even routine medical procedures.
A 2022 study in the Journal of Internal Medicine by the American Medical Association (JAMA) showed increased serious bleeding events in patients taking Xarelto® compared to those on Warfarin. The study specifically noted a higher risk of:
- Gastrointestinal bleeding (3.4% vs. 1.7%)
- Genitourinary bleeding (1.4% vs. 0.5%)
- Intracranial bleeding (0.5% vs. 0.3%)
These findings are concerning, highlighting the potential for the drug to cause significant internal bleeding complications.
Leveraging over a decade of data, researchers presented their findings on blood thinners at the 2023 American Society of Hematology meeting. This analysis compared the effectiveness and safety of three blood thinners: rivaroxaban (Xarelto), apixaban (Eliquis), and warfarin.
Dr. Jordan K. Schaefer, the study’s first author, noted that patients on Rivaroxaban had the highest bleeding rates, followed by Warfarin, with Apixaban having the lowest.
For 100 patients over one year, Rivaroxaban caused 40 bleeding events (this figure was 25 for Warfarin). Apixaban had fewer major bleeding incidents and a lower mortality rate than both Rivaroxaban and Warfarin. These findings could influence how providers select anticoagulants for patients.
Arkansas and the National Landscape of Xarelto® Lawsuits
The lawsuits claim the companies downplayed the increased risk of bleeding with Xarelto®, failing to adequately inform both patients and doctors.
They are also accused of downplaying the severity of potential bleeding complications in marketing materials. Another important allegation is that no readily available reversal agent was developed for Xarelto® bleeding events.
While several mass tort lawsuits were consolidated in West Virginia, individual cases are now proceeding through state courts nationwide.
Bayer is seen going all in and defending its hold on the Xarelto® market. In a recent development, a German court temporarily blocked sales of seven generic versions of the drug. This legal hurdle, however, is not the final step. The companies can challenge this decision before appealing to a higher court.
Legal Options for Arkansans Affected by Xarelto®
If you or someone you know in Arkansas has suffered a serious bleeding event while taking Xarelto®, you may have legal recourse. According to Keith Law Group, the liability claims could be due to:
- Defective drug manufacturing (improper production or tainted drugs)
- Drugs with dangerous side effects
- Improperly marketed drugs (no instructions regarding their correct usage).
Individuals who have experienced uncontrolled bleeding, internal bleeding, a stroke, or other complications due to bleeding may be eligible to pursue compensation. Consulting with a personal injury lawyer experienced in handling pharmaceutical litigation can provide valuable guidance on your legal options.
Recently, the community of Arkansas came forward, filing more than 100 lawsuits against Dr. Brian Hyatt, a psychiatrist from Rogers. Many former patients accused him of mistreatment, including coercion, over-medication, and wrongful detention.
Hiring a Rogers personal injury lawyer is the best option for these victims. These patients reported injuries ranging from chemical sedation and broken bones to physical abuse. Many have experienced consequences as severe as losing custody of their children. They have even lost jobs due to falsified medical records, and now fear medical care.
One patient’s mother, Brandie Kersey, described how her son was not properly medicated and communication with the medical staff was obstructed. More lawsuits are anticipated as additional former patients come forward.
Recent Updates and Ongoing Research
The conversation surrounding Xarelto®’s safety continues to evolve. In recent developments, the FDA approved AndexXa (andexanet alfa) as a reversal agent for Xarelto® bleeding events. However, its availability is limited to specific healthcare settings and may not be readily accessible in all emergencies.
Researchers are actively studying the long-term effects of Xarelto® and exploring the development of more accessible and effective reversal agents.
FAQs
As a Xarelto® consumer, how can I protect myself?
Be sure to discuss all potential benefits and risks associated with the medication, especially compared to other blood thinners available. It’s vital to disclose all medications you take, including over-the-counter drugs and supplements, as some can interact with Xarelto® and raise your bleeding risk. Be aware of signs and symptoms of unusual bleeding, such as bloody stools, dark urine, or excessive bruising.
Are there alternative blood thinners available besides Xarelto®?
Yes, there are other blood thinners available, such as Warfarin (Coumadin) and Apixaban (Eliquis). However they have their own benefits and risks, and the best pick for you would depend on your specific needs, and of course, your medical history. Taking blood thinners like Xarelto® thus requires an open dialogue with your doctor.
What are some lifestyle changes that reduce bleeding risks while taking Xarelto®?
Avoid activities with a high risk of injury like activities that involve sharp objects for example. Inform your dentist and doctor about all medications you take. This will help them avoid procedures or medications that could interact with Xarelto® and increase bleeding risk. A balanced and healthy diet will also promote healthy blood clotting.
Overall, this essay recognizes both the uses and the disadvantages of Rivaroxaban. While Xarelto® can be a valuable tool for preventing blood clots, the potential for serious bleeding complications necessitates careful consideration of its use with your doctor. For Arkansans on Xarelto®, close monitoring by your doctor is crucial to ensure its continued benefit outweighs the risks.
